Lepto

[KeeperBoy]

Do you vaccinate against lepto with the dhpp shot?

I don't give it to either of my two. In our situation the risk outweighs the benefit.

[Ron]

nope i've never vaccinated against it. It's so uncommon, that i just don't see the need

[KeeperBoy]

Apparently at our new vet it is standard to put lepto in with the distemper. Our old vet always asked. I guess many vets give a DHLPP unless a DHPP is requested. I'm so glad I said something about not giving my guys lepto, or else they would have gotten it. I wonder if it has anything to do with geographic location?

I've read stories of show dogs have their face paralyzed after the lepto vaccine and never being able to be shown again. Boo is already a vaccine reactor and with the high risk of cancer in boxers I can't see giving either dog something they don't really need.

[cinnamon12]

I Lived in Pennsylvania in the city and my late boxer got leptospirosis. She was sick one day and dead the next. I took her to the vet but it was to late her kidneys had already started to shut down. You don't have to live in the country for your animal to contract this terrible disease. It's very important to have your animal vacinated.

[KeeperBoy]

http://doglady1.tripod.com/scribe/id5.html

An interesting link about vaccines.

And another...

http://www.minschnauzer.com/health/vaccinations.html

[Kris L. Christine]

You might find the information below helpful in deciding whether or not to vaccinate your boxer against Lepto.

Regarding the Lepto vaccine, on Page 2 of the American Animal Hospital Association's 2003 Canine Vaccine Guidelines and Recommendations, it states that "Optional or 'noncore' vaccines are those that the committee believe should be considered only in special circumstances because their use is more dependent on the exposure risk of the individual animal. Issues of geographic distribution and lifestyle should be considered before administering these vaccines. In addition, the diseases involved are generally self-limiting or respond readily to treatment. The committee believes this group of vaccines comprises distemper-meases virus (D-MV), canine parainfluenza virus (CPIV), Leptospira spp., Bordetella bronchispetica, and Borrelia burdorferi."

Furthermore, on Page 7, Tables 1 of the AAHA Guidelines referenced above, it states under Revaccination (Booster Recommendations) that the Leptospira interrogans vaccine "....this product carries high-risk for adverse vaccine events." Under Overall Comments and Recommendations they elaborate: "Anecdotal reports from veterinarians and breeders suggest that the incidence of postvaccination reactions (acute anaphylaxis) in puppies (<12 wks of age) and small-breed dogs is high. Reactions are most severe in young (<9 wks of age) puppies. Routine use of the vaccine should be delayed until dogs are >9 wks of age."

On Page 8 of the 2006 American Animal Hospital Association's Canine Vaccine Guidelines, it states that "Veterinarians are advised of anecdotal reports of ACUTE ANAPHYLAXIS in TOY BREEDS following administration of leptospirosis vaccines. Routine vaccination of toy breeds should only be considered in dogs known to have a high exposure risk."

Leptospira is a “killed” vaccine and is associated with clinically significant adverse reactions. According to the 2003 AAHA Guidelines http://www.leerburg.com/special_report.htm (Page 16), "...killed vaccines are much more likely to cause hypersensitivity reactions (e.g., immune-mediated disease)." Further, the AAHA task force reports on Page 18 that, "Bacterial vaccines, especially killed whole organism products …..are much more likely to cause adverse reactions than subunit or live bacterial vaccines or MLV vaccines, especially if given topically. Several killed bacterial products are used as immunomodulators/adjuvants. Thus, their presence in a combination vaccine product may enhance or suppress the immune response or may cause an undesired response (e.g., IgE hypersensitivity or a class of antibody that is not protective)."

A fuller discussion of the Lepto vaccine can be found on Page 14, in which it is reported that, "Immunity is an ill-defined term for Leptospira ssp. products. If immunity is defined as protection from infection or prevention of bacterial-shedding, then there is little or no enduring immunity."

Personally, I found the most stunning quote in this entire document to be on Page 18, in which the task force declares: "However, the ethical issue that our profession struggles with today is whether economics justifies giving an animal a drug (vaccines are biologic drugs) that is not necessarily required. As a minimum, we should allow pet owners to make this choice rather than make it for them."

Dr. Alice Wolf, Professor of Small Animal Internal Medicine at Texas A&M College of Veterinary Medicine, stated in an address (Vaccines of the Present and Future http://www.vin.com/VINDBPub/SearchPB...00/PR00141.htm) at the 2001 World Small Animal Veterinary Association World Congress that: "The most reactive vaccines for dogs include leptospirosis bacterin and Borrelia [Lyme]vaccine.".

The Leptospira vaccine is also an "adjuvanted" vaccine, as are the Lyme and Rabies vaccines. "The World Health Organization (WHO) in 1999 classified veterinary vaccine adjuvants as Class III/IV carcinogens with Class IV being the highest risk," IARC Monographs on the Evaluation of Carinogenic Risks to Humans: Volune 74, World Health Organization, International Agency for Research on Cancer, Feb. 23-Mar. 2, 1999, p. 24, 305, 310.

Combination Vaccines, Multiple Shots--on Page 16 of the 2003 AAHA Guidelines under Immunological Factors Determining Vaccine Safety, it states that: "Although increasing the number of components in a vaccine may be more convenient for the practitioner or owner, the likelihood for adverse effects may increase. Also, interference can occur among the components. Care must be taken not to administer a product containing too many vaccines simultaneously if adverse events are to be avoided and optimal immune responses are sought. "
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Duration of Immunity: The Rabies Vaccine Challenge - Show #185 Animal Talk Radio Show 7/30/08 http://www.blogtalkradio.com/animalt...lenge-Show-186

Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz http://www.cedarbayvet.com/duration_of_immunity.htm

What Everyone Needs to Know about Canine Vaccines, Dr. Ronald Schultz
http://www.puliclub.org/CHF/AKC2007C...20Vaccines.htm

Vaccination: An Overview Dr. Melissa Kennedy, DVM360 http://veterinarycalendar.dvm360.com....jsp?id=568351

World Small Animal Veterinary Association 2007 Vaccine Guidelines http://www.wsava.org/SAC.htm Scroll down to Vaccine Guidelines 2007 (PDF)

The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at http://www.leerburg.com/special_report.htm .

The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at http://www.aahanet.org/PublicDocumen...s06Revised.pdf .

Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at http://www.newvaccinationprotocols.com/

October 1, 2002 DVM Newsletter article entitled, AVMA, AAHA to Release Vaccine Positions, http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=35171

July 1, 2003 DVM Newsletter article entitled, What Do We Tell Our Clients?, Developing thorough plan to educate staff on changing vaccine protocols essential for maintaining solid relationships with clients and ensuring quality care http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61696

July 1, 2003, DVM Newsletter article, Developing Common Sense Strategies for Fiscal Responsibility: Using an interactive template to plan service protocol changes http://www.dvmnewsmagazine.com/dvm/a...l.jsp?id=61694

Animal Wellness Magazine Article Vol. 8 Issue 6, How Often Does he REALLY Need A Rabies Shot Animal Wellness Magazine - devoted to natural health in animals

The Rabies Challenge Animal Wise Radio Interview
Listen to Animal Wise (scroll down to The Rabies Challenge 12/9/07)

The Vaccine Challenge Animal Talk Naturally Online Radio Show » The Vaccine Challenge - Show #91

Rabies Shot Killed my Poodle May 28, 2008 Channel 5 News WCVB http://www.thebostonchannel.com:80/n...ss=bos&taf=bos

US Declared Canine-Rabies Free -- CDC Announces at Inaugural World Rabies Day Symposium CDC Press Release - September 7, 2007

Rabies Prevention -- United States, 1991 Recommendations of the Immunization Practices Advisory Committee (ACIP), Center for Disease Control's Morbidity and Mortality Weekly March 22, 1991 / 40(RR03);1-19 http://www.cdc.gov/mmwr/preview/mmwrhtml/00041987.htm "A fully vaccinated dog or cat is unlikely to become infected with rabies, although rare cases have been reported (48). In a nationwide study of rabies among dogs and cats in 1988, only one dog and two cats that were vaccinated contracted rabies (49). All three of these animals had received only single doses of vaccine; no documented vaccine failures occurred among dogs or cats that had received two vaccinations. "

[bruinsBoxers]

As with all vaccines you have to weigh the pros and cons .
If you live in a high risk area where there are lots of cases of lepto or have dogs that run in the woods and drink from streams . Only you can decide whether the risk of giving the vaccine is worth it .

And yes there will always be cases of pets who don't fit into the regular risk zone that do contract the illness .

[Kris L. Christine]

Absolutely, dog owners must (with their veterinarian's input) assess their animal's particular risk of disease exposure and the risk of vaccinal adverse reactions. There is no one-size fits all.